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An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells.
Vinogradova EV, Zhang X, Remillard D, Lazar DC, Suciu RM, Wang Y, Bianco G, Yamashita Y, Crowley VM, Schafroth MA, Yokoyama M, Konrad DB, Lum KM, Simon GM, Kemper EK, Lazear MR, Yin S, Blewett MM, Dix MM, Nguyen N, Shokhirev MN, Chin EN, Lairson LL, Melillo B, Schreiber SL, Forli S, Teijaro JR, Cravatt BF. Vinogradova EV, et al. Among authors: konrad db. Cell. 2020 Aug 20;182(4):1009-1026.e29. doi: 10.1016/j.cell.2020.07.001. Epub 2020 Jul 29. Cell. 2020. PMID: 32730809 Free PMC article.
7-Dehydrocholesterol is an endogenous suppressor of ferroptosis.
Freitas FP, Alborzinia H, Dos Santos AF, Nepachalovich P, Pedrera L, Zilka O, Inague A, Klein C, Aroua N, Kaushal K, Kast B, Lorenz SM, Kunz V, Nehring H, Xavier da Silva TN, Chen Z, Atici S, Doll SG, Schaefer EL, Ekpo I, Schmitz W, Horling A, Imming P, Miyamoto S, Wehman AM, Genaro-Mattos TC, Mirnics K, Kumar L, Klein-Seetharaman J, Meierjohann S, Weigand I, Kroiss M, Bornkamm GW, Gomes F, Netto LES, Sathian MB, Konrad DB, Covey DF, Michalke B, Bommert K, Bargou RC, Garcia-Saez A, Pratt DA, Fedorova M, Trumpp A, Conrad M, Friedmann Angeli JP. Freitas FP, et al. Among authors: konrad db. Nature. 2024 Feb;626(7998):401-410. doi: 10.1038/s41586-023-06878-9. Epub 2024 Jan 31. Nature. 2024. PMID: 38297129
A concise synthesis of tetrodotoxin.
Konrad DB, Rühmann KP, Ando H, Hetzler BE, Strassner N, Houk KN, Matsuura BS, Trauner D. Konrad DB, et al. Science. 2022 Jul 22;377(6604):411-415. doi: 10.1126/science.abn0571. Epub 2022 Jul 21. Science. 2022. PMID: 35862530
In Vivo Photopharmacology Enabled by Multifunctional Fibers.
Frank JA, Antonini MJ, Chiang PH, Canales A, Konrad DB, Garwood IC, Rajic G, Koehler F, Fink Y, Anikeeva P. Frank JA, et al. Among authors: konrad db. ACS Chem Neurosci. 2020 Nov 18;11(22):3802-3813. doi: 10.1021/acschemneuro.0c00577. Epub 2020 Oct 27. ACS Chem Neurosci. 2020. PMID: 33108719 Free PMC article.
21 results